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Dr. Fernando López Gallego

Paseo Miramon 182,
San Sebastián-Donostia, 20012, Spain

www.cicbiomagune.es

Research Professor Dr. Fernando López Gallego,
supervisor of ESR3 and ESR8, and WP2 “Systematic Assembly of Heterogeneous (Bio)Catalysts” Leader, is IKERBASQUE research professor at CICbiomaGUNE (San Sebastián, Spain). Dr. López-Gallego has a consolidate expertise applying multienzyme systems to biotechnological processes by harnessing the exquisite selectivity of enzymes (biological catalysts). In this context, he has mimicked the spatial organization found inside the living organisms, but using ex-vivo systems supported on solid materials. To address such goal, his group is bridging the chemistry and the biology utilizing multidisciplinary tools that involve molecular biology, enzymology and material chemistry. As results of this scientific activity he has published 103 peer reviewed publications in international journals which have had an important impact on the scientific community as it demonstrated by an h-index of 33.

Key Research Facilities, Infrastructure and Equipment
Each Principal Investigator at CIC has his own general laboratory to perform chemical/biochemical work. General equipment to which the researchers involved in the proposal have full access include: Analytical facilities, including NMR, HPLC-MS, GC-MS, UV-Vis, FTIR, etc. state-of the art Biochemical/Enzymology facilities  and Molecular imaging Facility including radio-HPLC, radio-GC, radio-TLC, gamma spectrometry, PET-CT, SPECT-CT and autoradiography.

Hosting University: CIC biomaGUNE
The Centre for Cooperative Research in Biomaterials (CICbiomaGUNE) is a non-profit research organization with the basic aim of creating, producing, promoting and applying cooperative scientific research and technological innovation in the biomaterials field. The Centre is composed of 13 international research teams conducting state-of-the-art research at the interface between chemistry, physics and biology, with particular emphasis on the properties and applications of molecular-level biological nanostructures. CICbiomaGUNE’ cutting-edge infrastructures include the Molecular Imaging Facility. CICbiomaGUNE has a large expertise in collaborative research and training programmes at international level, through its participation in numerous international projects in the last 5 years: > 80 national projects and >40 EU research and training actions, including 6 ERC grants, 20 Marie Curie projects and 15 collaborative projects. Also during the last 5 years > 40 PhD students have defended their thesis and > 60 postdoctoral researchers have received scientific training at CICbmG. The center has a well established academic relationship with the University of Basque Country (UPV/EHU) which awards the PhD titles of many students who develop their thesis project under the supervision of CIC biomaGUNE researchers.

Relevant Publications and/or Research / Innovation Product

  1. S. Velasco‐Lozano, J. Santiago-Arcos, José A. Mayoral, and F. López-Gallego.  Co‐immobilization and Colocalization of Multi‐Enzyme Systems for the Cell‐Free Biosynthesis of Aminoalcohols. Chemcatchem. 2020. https://doi.org/10.1002/cctc.201902404
  2. A.I. Benítez-Mateos, M. Contente, S. Velasco-Lozano, F. Paradisi, F. López-Gallego. Self-Sufficient Flow-biocatalysis by co-immobilization of pyridoxal 5′-phosphate and ω-transaminases onto porous carriers. ACS Sustainable Chemistry & Engineering. 2018. 6, (10), 13151-13159.
  3. S. Velasco-Lozano, A. I. Benítez-Mateos, F. López-Gallego. Co-immobilized PhosphorylatedCofactors and Enzymes as Self- Sufficient Heterogeneous Biocatalysts for Chemical Processes, Angew. Chem. Int. Ed., 2017, 56, 771-775.

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