PUBLICATIONS

Scientific Paper

Assessing the Industrial Edge of the Lipase-Mediated Oxidation of 2,5-Diformylfuran to 2,5-Furandicarboxylic Acid: Rotating Bed Reactors, an “Acyl-Donor-Free” Oxidation Concept, and Environmental Aspects

Milica Milić, Guillem Vernet, Hai Yen Le, Ningning Zhang, Emil Byström, Pablo Domínguez de María, Selin Kara Organic Process Research & Development

Scientific Paper

Immobilised Alcohol Dehydrogenase and Ene-Reductase Work in Concert to Reduce Cyclohex-2-enone in Bulk Organic Solvent

Antía Pintor, Alexey Volkov, Iván Lavandera & Vicente Gotor-Fernández ChemCatChem 2024, 16, e202400416.

Scientific Paper

Design of 3D-Printed Heterogeneous Reactor Systems To Overcome Incompatibility Hurdles when Combining Metal and Enzyme Catalysis in a One-Pot Process

Nadiya Salitra, Jonas Gurauskis & Harald Gröger Angew. Chem. Int. Ed. 2024, 63, e202316760.

Scientific Paper

Integrated preservation of water activity as key to intensified chemoenzymatic synthesis of bio-based styrene derivatives

Philipp Petermeier, Jan Philipp Bittner, Tobias Jonsson, Pablo Domínguez de María, Emil Byström & Selin Kara Communications Chemistry volume 7, Article number: 57 (2024)

Scientific Paper

Selective Oxidation of 5-Hydroxymethylfurfural to 2,5-Diformylfuran in Biphasic Media using Immobilized Galactose Oxidase: Proof of Concept and Limitations

Milica Milić, Emil Byström, Pablo Domínguez de María, Selin Kara ChemCatChem 2024, 16, e202301384.

Scientific Paper

Stability Increase of Phenolic Acid Decarboxylase by a Combination of Protein and Solvent Engineering Unlocks Applications at Elevated Temperatures

Kamela Myrtollari, Elia Calderini, Daniel Kracher, Tobias Schöngaßner, Stela Galušić, Anita Slavica, Andreas Taden, Daniel Mokos, Anna Schrüfer, Gregor Wirnsberger, Karl Gruber, Bastian Daniel, and Robert Kourist ACS Sustainable Chem. Eng. 2024, 12, 9, 3575–3584.

Book Chapter

Chapter 11 – Versatility of microbial laccases in industrial applications

Vincenzo Lettera, Nicoletta Cascelli, Addolorata De Chiaro, Giovanni Sannia Progress in Biochemistry and Biotechnology, 2024, Pages 263-332.

Scientific Paper

Biotransamination of Furan-Based Aldehydes with Isopropylamine: Enzyme Screening and pH Influence

Antía Pintor, Nicoletta Cascelli, Alexey Volkov, Vicente Gotor-Fernández and Iván Lavandera ChemBioChem 2023, 24, e202300514.

Scientific Paper

Spectrophotometric Assay for the Detection of 2,5-Diformylfuran and Its Validation through Laccase-Mediated Oxidation of 5-Hydroxymethylfurfural

Nicoletta Cascelli, Vicente Gotor-Fernández, Iván Lavandera, Giovanni Sannia and Vincenzo Lettera Int. J. Mol. Sci. 2023, 24, 16861.

Scientific Paper

Heterogeneous biocatalytic reduction of 5-(hydroxy)methyl furfural using two co-immobilised alcohol dehydrogenases

Jakub F. Kornecki, André Pick, Pablo Dominguez de María and Fernando López-Gallego RSC Sustain., 2023, 1, 1883-1895.

Scientific Paper

Development of an amine transaminase-lipase cascade for chiral amide synthesis under flow conditions

Antía Pintor, Ashley P. Mattey, Iván Lavandera, Vicente Gotor-Fernández and Alexey Volkov Green Chem., 2023,25, 6041-6050.

Scientific Paper

Chemoselective Lipase-Catalyzed Synthesis of Amido Derivatives from 5-Hydroxymethylfurfurylamine

Antía Pintor, Iván Lavandera, Alexey Volkov, and Vicente Gotor-Fernández ACS Sustainable Chem. Eng. 2023, 11, 28, 10284–10292

Scientific Paper

FTIR microscopy for direct observation of conformational changes on immobilized ω-transaminase: effect of water activity and organic solvent on biocatalyst performance

Iulia-Ioana Rădoi, Diana Eva Bedolla, Lisa Vaccari, Anamaria Todea, Federico Zappaterra, Alexey Volkov, Lucia Gardossi, Catal. Sci. Technol., 2023

Scientific Paper

Biosynthesis of Furfurylamines in Batch and Continuous Flow by Immobilized Amine Transaminases

Heinks, Tobias, Luisa M. Merz, Jan Liedtke, Matthias Höhne, Luuk M. van Langen, Uwe T. Bornscheuer, Gabriele Fischer von Mollard, and Per Berglund. 2023. Catalysts 13, no. 5: 875.

Scientific Paper

Spectrophotometric and fluorimetric high-throughput assays for phenolic acid decarboxylase

Henrik Terholsen, Kamela Myrtollari, Mirna Larva, Christina Möller, Andreas Taden, Robert Kourist, Uwe T. Bornscheuer, Daniel Kracher
ChemBioChem 2023, e202300207.

Milica Milić, Pablo Domínguez de María and Selin Kara.
EFB Bioeconomy Journal 3 (2023) 100050

Scientific Paper

Laccases from Pleurotus ostreatus applied to the oxidation of furfuryl alcohol for the synthesis of key compounds for polymer industry.

Nicoletta Cascelli, Vincenzo Lettera, Giovanni Sannia, Vicente Gotor-Fernández, Ivan Lavandera
ChemSusChem 2023, e202300226.

Scientific Paper

2,5-Furandicarboxaldehyde as a bio-based crosslinking agent replacing glutaraldehyde for covalent enzyme immobilization

Chiara Danielli, Luuk van Langen, Deborah Boes, Fioretta Asaro, Serena Anselmi, Francesca Provenza, Monia Renzi, Lucia Gardossi,
RSC Advances, 2022, 55 (12), 35676-35684.

Scientific Paper

A multiplex assay to assess the transaminase activity toward chemically diverse amine donors

Nicolette Czarnievicz, Maria Grazia Rubanu, Maialen Iturralde, Jesús Albarran-Velo, Eleftheria Diamanti, Vicente Gotor Fernández, Maciej Skolimowski, Fernando López-Gallego
ChemBioChem. 2022

Scientific Paper

The role of buffer, pyridoxal 5’-phosphate and light on the stability of the Silicibacter pomeroyi transaminase

Luisa M. Merz, Luuk M. van Langen, Per Berglund
ChemCatChem. 2022

Scientific Paper

Design of a green chemoenzymatic cascade for scalable synthesis of bio-based styrene alternatives

Philipp Petermeier, Jan Philipp Bittner, Simon Müller, Emil Byström, Selin Kara
Green Chem. 2022

Scientific Paper

Enzymatic Cascade for the Synthesis of 2,5-Furandicarboxylic Acid in Biphasic and Microaqueous Conditions: ‘Media-Agnostic’ Biocatalysts for Biorefineries

Milica Milić, Dr. Emil Byström, Dr. Pablo Domínguez de María, Prof. Dr. Selin Kara
ChemSusChem2022,e202102704

PabloDomínguez de María
Current Opinion in Green and Sustainable Chemistry, Volume 31, October 2021, 100514.

Scientific Paper

Exploring the in Vitro Operating Window of Glycosyltransferase PtUGT1 from Polygonum tinctorium for a Biocatalytic Route to Indigo Dye

Philipp Petermeier, Cristina Fortuna, Kathrine M. Hübschmann, Gonzalo N. Bidart, Thomas Tørring, David Teze, Ditte H. Welner, and Selin Kara
ACS Sustainable Chem. Eng. 2021, 9, 25, 8497–8506.

Scientific Paper

PUBLICATIONS

Assessing the Industrial Edge of the Lipase-Mediated Oxidation of 2,5-Diformylfuran to 2,5-Furandicarboxylic Acid: Rotating Bed Reactors, an “Acyl-Donor-Free” Oxidation Concept, and Environmental Aspects

Immobilised Alcohol Dehydrogenase and Ene-Reductase Work in Concert to Reduce Cyclohex-2-enone in Bulk Organic Solvent

Design of 3D-Printed Heterogeneous Reactor Systems To Overcome Incompatibility Hurdles when Combining Metal and Enzyme Catalysis in a One-Pot Process

Integrated preservation of water activity as key to intensified chemoenzymatic synthesis of bio-based styrene derivatives

Selective Oxidation of 5-Hydroxymethylfurfural to 2,5-Diformylfuran in Biphasic Media using Immobilized Galactose Oxidase: Proof of Concept and Limitations

Stability Increase of Phenolic Acid Decarboxylase by a Combination of Protein and Solvent Engineering Unlocks Applications at Elevated Temperatures

Chapter 11 – Versatility of microbial laccases in industrial applications

Biotransamination of Furan-Based Aldehydes with Isopropylamine: Enzyme Screening and pH Influence

Spectrophotometric Assay for the Detection of 2,5-Diformylfuran and Its Validation through Laccase-Mediated Oxidation of 5-Hydroxymethylfurfural

Heterogeneous biocatalytic reduction of 5-(hydroxy)methyl furfural using two co-immobilised alcohol dehydrogenases

Development of an amine transaminase-lipase cascade for chiral amide synthesis under flow conditions

Chemoselective Lipase-Catalyzed Synthesis of Amido Derivatives from 5-Hydroxymethylfurfurylamine

FTIR microscopy for direct observation of conformational changes on immobilized ω-transaminase: effect of water activity and organic solvent on biocatalyst performance

Biosynthesis of Furfurylamines in Batch and Continuous Flow by Immobilized Amine Transaminases

Spectrophotometric and fluorimetric high-throughput assays for phenolic acid decarboxylase

Laccases from Pleurotus ostreatus applied to the oxidation of furfuryl alcohol for the synthesis of key compounds for polymer industry.

2,5-Furandicarboxaldehyde as a bio-based crosslinking agent replacing glutaraldehyde for covalent enzyme immobilization

A multiplex assay to assess the transaminase activity toward chemically diverse amine donors

The role of buffer, pyridoxal 5’-phosphate and light on the stability of the Silicibacter pomeroyi transaminase

Design of a green chemoenzymatic cascade for scalable synthesis of bio-based styrene alternatives

Enzymatic Cascade for the Synthesis of 2,5-Furandicarboxylic Acid in Biphasic and Microaqueous Conditions: ‘Media-Agnostic’ Biocatalysts for Biorefineries

Exploring the in Vitro Operating Window of Glycosyltransferase PtUGT1 from Polygonum tinctorium for a Biocatalytic Route to Indigo Dye

Simple Plug-In Synthetic Step for the Synthesis of (−)-Camphor from Renewable Starting Materials

Enzyme Cascade Design and Modelling

Enzyme Cascade Design and Modelling

CONTACT

Innovative Training Network – European Industrial Doctorates

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 860414.