Assoc. Prof. Dr. Iván Lavandera and Assoc. Prof. Dr. Vicente Gotor-Fernández
They are supervisors of ESR6 and ESR7. Dr. Gotor-Fernández is Graduate Manager and Dr. Lavandera is WP4 “Training” Leader. Both senior scientists are Organic Chemists, belonging to the Bioorganic research group at the University of Oviedo since 2008 (I.L.) and 2004 (V.G.-F.), and they are currently leading the area related to the development of enzyme-catalysed processes, mainly focusing on the design of efficient chemo- and multienzymatic cascades.
After his PhD defense in 2003 at the University of Oviedo, Dr. Lavandera remained as post-doc in the Bioorganic research group until he moved to the University of Graz in 2005 to perform a post-doctoral stay with Prof. Wolfgang Kroutil. He returned to Oviedo in 2008 and since then he joined the Bioorganic research group as Clarín research fellow first, then as Ramón y Cajal research fellow, and finally as Associate Professor since 2015, getting his final habilitation on November 2017. He has published so far 86 journal articles, 11 book chapters, and 4 review articles. Dr. Gotor-Fernández performed his PhD at the University of Oviedo in 2001, and moving in 2002 to the University of Edinburgh as a Marie Curie postdoctoral researcher working Prof. Nicholas J. Turner. He returned to Oviedo in 2004 as Juan de la Cierva research fellow first, then as Ramón y Cajal research fellow and finally obtaining his habilitation as Associate Professor in 2012. He has published so far 124 journal articles, 11 book chapters, and 14 review articles.
Key Research Facilities, Infrastructure and Equipment
UNIOVI laboratories are fully equipped to carry out organic synthesis, perform biocatalytic processes, basic microbiology experiments and analytical development. Specific equipment available to this project includes among others HPLC chromatographs for analytical and preparative uses, GC chromatographs, UV spectrophotometers, orbital shakers or centrifuges, lyophilizers. In addition, the University of Oviedo (UNIOVI) provides technical support through its Scientifical and Technical Resource Department providing access to several techniques such as NMR, GC-MS, thermogravimetric analysis, X-ray diffraction analysis, etc.
Hosting University: University of Oviedo
The Bioorganic Research group at UNIOVI has a strong background in the development of selective enzymatic methodologies devoted to the preparation of organic molecules with special interest for those optically active. UNIOVI has a great expertise in organic synthesis, optimization of biocatalytic conditions and development of concurrent catalyzed processes. The group is a member of the University Institute of Biotechnology of Asturias (IUBA), collaborating with other groups of the university in order to improve the multidisciplinary research in the field of biotechnology and having access to a variety of devices related to molecular biology projects.
Relevant Publications and/or Research / Innovation Product
- D. Méndez-Sánchez, Á. Mourelle-Insua, V. Gotor-Fernández, I. Lavandera. Synthesis of α-alkyl-β-hydroxy amides through biocatalytic dynamic kinetic resolutions employing alcohol dehydrogenases. Adv. Synth. Catal. 2019, 361, 2706.
- Á. Mourelle-Insua, Lavandera, V. Gotor-Fernández. A designer natural deep eutectic solvent to recycle the cofactor in alcohol dehydrogenase-catalysed processes. Green Chem. 2019, 21, 2946.
- L. Martínez-Montero, V. Gotor, V. Gotor-Fernández, I. Lavandera. Mild chemoenzymatic oxidation of allylic sec-alcohols. Application to biocatalytic stereoselective redox isomerizations. ACS Catal. 2018, 8, 2413.