Prof. Dr. Lucia Gardossi

Dipartimento di Scienze Chimiche e Farmaceutiche
Università degli Studi di Trieste, Via Licio Giorgieri 1, 34127 Trieste – Italy

In silico rational enzyme engineering and screening
Stability and stabilization of native and immobilized enzymes for industrial applications

Prof. Dr. Lucia Gardossi, will contribute with training in biocatalysis, enzyme technology, sustainable and bio-based chemistry, bioeconomy for the supervision of ESR4 and ESR11. She is WP3 “Reaction Engineering, Process Optimization and Up-Scaling” Leader and chair of Gender Committee, responsible for the gender dimension of the project. She will contribute with her experience in the field of biocatalysis and sustainable chemistry (since 1988), acquired also at MIT (USA) and in industry. Moreover, L. Gardossi will provide the project with the awareness of the global scenario on sustainble and bio-based chemistry acquired as member of EU and national boards (H2020 and National Clusters). In the same research group Prof. Fioretta Asaro has >20y experience in advanced spectroscopy. Dr. Sara Fortuna, PhD in Theoretical and Computational Chemistry (Univ. Warwick, UK) is lecturer and junior principal investigator and she will be involved in the training of ESRs on the computational analysis of biocatalysts. Prof. Pierluigi Barbieri, of the Environmental Chemistry Lab, will contribute with training activities on Life Cycle Assessment.

Key Research Facilities, Infrastructure and Equipment
The Department has research labs for global 2000m2, full experimental facilities for biocatalysis, enzyme technology, biotransformations and organic synthesis, analytic and spectroscopic equipment (HPLC with PDA; GC; NMR 500 and 400 MHz, ESI mass spectrometry, diffrattometer, CD, IR, Raman, UV-Vis, polarimeter, DSC) computational facilities for statistical studies and work-stations for molecular modelling of enzymes. DSCF has access to ELETTRA-Synchrotrone (Trieste) for high resolution macro-molecule and advanced characterization of the immobilized enzymes (morphologic and spectroscopic). The Department is managed by an administrative and financial office and has permanent qualified technical staff (globally 17 employees). University of Trieste has an Industrial Liaison Office that works at the interface between scientists and industries, taking care of IP and legal issues.

Hosting University: University of Trieste
The University of Trieste (UNITS) has a student population of about 16,000. It offers a wide range of educational programs at bachelor, master and doctoral level as well as short vocational masters, advanced masters and specialisation programs. Some degree programs are taught in English. The university is part of a lively and coordinated regional research environment, comprising more than 40 research institutions, involving more than 9000 scientists. A Welcome Office FVG, jointly developed by the scientific and academic institutions of Friuli Venezia Giulia, offers a wide range of helpful services and useful information to international students and researchers coming from all over the world about the arrival and stay in the Region through this website and two info points

Relevant Publications and/or Research / Innovation Product

  1. M. Cespugli, S. Lotteria, C. Ebert, L. Gardossi. Rice Husk as an Inexpensive Renewable Im-mobilization Carrier for Biocatalysts Employed in the Food, Cosmetic and Polymer Sectors. Catalysts 2018, 8, 471.
  2. A. Pellis, V. Ferrario, M. Cespugli, L. Corici, A. Guarneri, B. Zartl, E.H. Acero, C. Ebert, G.M. Guebitz, L. Gardossi. Fully renewable polyesters via polycondensation catalyzed by Thermobifida cellulosilytica cutinase 1: an integrated approach. Green Chem., 2017, 19, 490-502.