Newest Publication with contribution by Kamela Myrtollari

Congratulations to Kamela Myrtollari, Andreas Taden and Robert Kourist for their joint contribution to a new publication in which it is discuss how a biosynthesis route for the polymer precursor tulipalin A starting from isoprenyl acetate is proposed. “The alkane monooxygenase AlkB catalyzes the chemoselective terminal hydroxylation of isoprenyl acetate. Rational enzyme engineering further increased the activity of the membrane enzyme. An alcohol and aldehyde dehydrogenase pair enabled complete oxidation to the carboxylic acid, thus paving the way to biotechnological tulipalin A production.” An interesting read so check it out

Title: Engineering of Transmembrane Alkane Monooxygenases to Improve a Key Reaction Step in the Synthesis of Polymer Precursor Tulipalin A

Andrea Nigl, Veronica Delsoglio , Lucija Sovic, Marina Grgić , Lenny Malihan-Yap, Kamela Myrtollari , Jelena Spasic, Margit Winkler , Gustav Oberdorfer, Andreas Taden , Iva Anić, Robert Kourist , Angewandte Chemie

English version: https://doi.org/10.1002/anie.202503464

German version: https://onlinelibrary.wiley.com/doi/10.1002/ange.202503464